Uống bia rượu làm tăng nguy cơ mắc hơn 60 bệnh, trong đó có nhiều bệnh trước đây không liên quan đến rượu

 Uống bia rượu làm tăng nguy cơ mắc hơn 60 bệnh ở nam giới Trung Quốc, bao gồm nhiều bệnh trước đây không liên quan đến bia rượu, theo một nghiên cứu mới của các nhà nghiên cứu từ Đại học Y Oxford và Đại học Bắc Kinh, được công bố trên Tạp chí Y học Nature Medicine.

https://medicalxpress.com/news/2023-06-population-health-alcohol-consumption-diseases.html

Key findings:

• Among 207 diseases studied, self-reported alcohol intake was associated with higher risks of 61 diseases in men. This included 28 diseases previously established by the World Health Organization as alcohol-related, such as liver cirrhosis, stroke, and several gastrointestinal cancers, and 33 diseases not previously established as alcohol-related, such as gout, cataract, some fractures, and gastric ulcer;
• There were over 1.1 million hospitalizations recorded in the study, and men who had ever drank alcohol regularly had significantly higher risk of developing any disease and experienced more frequent stays in hospital, compared with men who had only drunk alcohol occasionally;
• Certain drinking patterns, such as drinking daily, drinking in heavy "binge" episodes, or drinking outside mealtimes, particularly increased the risks of certain diseases, particularly liver cirrhosis;
• In the genetic analyses, there was evidence for a dose-dependent causal effect on the identified alcohol-related diseases collectively, with every four drinks per day associated with a 14% higher risk of established alcohol-related diseases, 6% higher risk of diseases not previously known to be alcohol-related, and over two-fold higher risk of liver cirrhosis and gout;
• In the genetic analyses, higher alcohol intake was significantly associated with higher risk of stroke in a dose-response manner (consistent with previous findings in the CKB study), but showed no increased risk with ischemic heart disease (IHD). Moreover, moderate drinking (ie one-two drinks/day) did not have any protective effects against IHD;
• As few women in China drink alcohol (less than 2% of women in the study drank regularly), women in this study provided a useful control group in the genetic analyses, which helped confirm that the excess disease risks in men were caused by drinking alcohol, not by some other mechanisms related to the genetic variants.